The Symbionics Perspectief Program is a Dutch research program funded by Technology Foundation STW, leaded by prof. Bart Koopman. The objective of the Symbionics program is to create systems that co-adapt automatically, which is expressed in the term ‘symbionic’, either intrinsically by design, or by control, or their combination. Furthermore, we aim to create assistive devices that completely fit underneath regular clothing, which is key to social acceptance. Achieving these objectives will require a mind shift in rehabilitation and technology. The program is designed such that the end-users have a central role in defining the requirements and priorities for developing the assistive devices.